Metabolic and Antirheumatic Activities of 6-Methyl-prednisolone (Medrol)
نویسندگان
چکیده
منابع مشابه
Metabolic and antirheumatic activities of 6-methylprednisolone (medrol).
During the past few years a concerted effort has been made to develop synthetic derivatives of hydrocortisone and cortisone which would retain their anti-inflammatory activity but would be devoid of certain of their unwanted physiologic effects. Hope that analogues with enhanced therapeutic indices could be synthesized has stemmed from the knowledge that several properties of the naturally occu...
متن کامل6-Methyl Prednisolone in the Treatment of Rheumatoid Arthritis
IN recent years synthetic analogues of cortisone and hydrocortisone have been employed in the treatment of rheumatoid arthritis. Prednisone and prednisolone were first used by Bunim, Pechet, and Bollet in 1955, and since then further reports Although the greater anti-rheumatic effects and lessened risks of sodium retention in these compounds have been advantageous, most workers have been concer...
متن کاملNiacin Exacerbates Methyl Prednisolone-Induced Bone Changes in Growing Rats
Positive role of niacin on serum lipid profile of rats treated with glucocorticoids (GCs) has been reported. This study aims to evaluate effect of niacin on bone changes in GC-induced dyslipidemic rats. A number of 28 growing rats divided into four groups and treated as control, Methyl prednisolone (MP) group (3.5 mg/kg five days a week, SC); MPN group (MP + niacin 200 mg/kg/day orally) and MPA...
متن کاملDEPO-MEDROL Label
Each mL of these preparations contains: Methylprednisolone acetate.............................. 20 mg Polyethylene glycol 3350....................................29.5 mg Polysorbate 80 ....................................................1.97 mg Monobasic sodium phosphate ..............................6.9 mg Dibasic sodium phosphate USP..........................1.44 mg Benzyl alcohol added as a...
متن کاملthe effects of cooperative versus individual directed reading thinking activities on students inferential and referential questions
two groups of students were assigned as experimental and control ones, and were given instruction on directed reading-thinking activities and after some treatment, they were post-tested. although the initial pre-test did not show any significant differences, the final post-test result revealed that the cooperative reading comprehension helped the experimental group. the cooperative students’...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1957
ISSN: 0003-4967
DOI: 10.1136/ard.16.3.297